Microorganisms and Disease
Which of the following characteristic of the Rotavirus was important for the construction of the Rotashield vaccine?

A limited number of capsule types
The ability of monkey Rotavirus strains to cause serious illness (diarrhea) in human beings
The possession of a segmented RNA genome
The ability of the Rotavirus to be transmitted faster

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Microorganisms and Disease
Type III secretion systems are used to inject "effector" proteins directly into a host cell. Salmonella uses a type III secretion system to help the pathogen to

secrete LT (heat labile toxin) and ST (heat stable toxin) into the lumen of the intestine
activate T cells to proliferate and secrete cytokines
survive within macrophages
survive the acid pH of the stomach

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Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

Both organisms cause skin and respiratory tract infections
Diphtheria toxin and edema toxin are ADP ribosylating toxins
The most serious disease symptoms are the direct result of toxin action
Both organisms are gram-positive spore formers

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Microorganisms and Disease
What is common in catheters and ventilators?

They bypass important defenses of the body
They predispose patients to viral rather than bacterial infections
They are used primarily in neonatal intensive care units
Bacteria responsible for associated infections are usually susceptible to antibiotics

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