Microorganisms and Disease
Which of the following characteristic of the Rotavirus was important for the construction of the Rotashield vaccine?

The possession of a segmented RNA genome
The ability of monkey Rotavirus strains to cause serious illness (diarrhea) in human beings
A limited number of capsule types
The ability of the Rotavirus to be transmitted faster

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Microorganisms and Disease
A major difference between EHEC and EPEC is

EPEC passes through the placenta to infect the fetus and EHEC does not
EPEC rearranges host cell actin and EHEC does not
EHEC possesses a type III secretion system and EPEC does not
EHEC secretes a Shiga-like toxin and EPEC does not

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

cause ADP ribosylation of a factor involved in protein synthesis
forms cAMP that leads to fluid accumulation
lysis macrophages with the release of cytokines
binds host cell receptors found on heart cells

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Microorganisms and Disease
Plastic implants can pose a serious nosocomial infection problem because

phagocytes have trouble engulfing bacteria embedded in a biofilm
All of these
phagocytes have trouble moving on the plastic surface
infected implants usually have to be surgically removed

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