Microorganisms and Disease
Plastic implants can pose a serious nosocomial infection problem because

infected implants usually have to be surgically removed
phagocytes have trouble engulfing bacteria embedded in a biofilm
phagocytes have trouble moving on the plastic surface
All of these

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Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

Both organisms cause skin and respiratory tract infections
The most serious disease symptoms are the direct result of toxin action
Diphtheria toxin and edema toxin are ADP ribosylating toxins
Both organisms are gram-positive spore formers

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Microorganisms and Disease
Cholera toxin is an A-B type toxin in which the B portions bind to a receptor on a host cell and the A portion enters the cell to cause

ADP ribosylation of adenylate cyclase that stops production of cAMP
ADP ribosylation of a G protein that locks it into an active form that stimulates adenylate cyclase to make cAMP
cleavage of rRNA that results in disruption of ribosome function
ADP ribosylation of guanylate cyclase that stimulates production of cGMP

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