Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

The most serious disease symptoms are the direct result of toxin action
Diphtheria toxin and edema toxin are ADP ribosylating toxins
Both organisms are gram-positive spore formers
Both organisms cause skin and respiratory tract infections

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Microorganisms and Disease
Plastic implants can pose a serious nosocomial infection problem because

phagocytes have trouble moving on the plastic surface
infected implants usually have to be surgically removed
phagocytes have trouble engulfing bacteria embedded in a biofilm
All of these

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

binds host cell receptors found on heart cells
lysis macrophages with the release of cytokines
forms cAMP that leads to fluid accumulation
cause ADP ribosylation of a factor involved in protein synthesis

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Microorganisms and Disease
A major difference between EHEC and EPEC is

EPEC passes through the placenta to infect the fetus and EHEC does not
EPEC rearranges host cell actin and EHEC does not
EHEC secretes a Shiga-like toxin and EPEC does not
EHEC possesses a type III secretion system and EPEC does not

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