Microorganisms and Disease
The nature of the poliovirus gives for oral vaccination (satin vaccine) as part of the eradication programme is

small dosage of wild-type live viruses
heat killed virus
formalin-inactivated viruses
live attenuated strains of all three immunological types

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Microorganisms and Disease
Which of the following characteristic of the Rotavirus was important for the construction of the Rotashield vaccine?

The ability of monkey Rotavirus strains to cause serious illness (diarrhea) in human beings
The possession of a segmented RNA genome
A limited number of capsule types
The ability of the Rotavirus to be transmitted faster

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

forms cAMP that leads to fluid accumulation
cause ADP ribosylation of a factor involved in protein synthesis
binds host cell receptors found on heart cells
lysis macrophages with the release of cytokines

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Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

Diphtheria toxin and edema toxin are ADP ribosylating toxins
Both organisms are gram-positive spore formers
Both organisms cause skin and respiratory tract infections
The most serious disease symptoms are the direct result of toxin action

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