Microorganisms and Disease
What is common in catheters and ventilators?

They predispose patients to viral rather than bacterial infections
Bacteria responsible for associated infections are usually susceptible to antibiotics
They are used primarily in neonatal intensive care units
They bypass important defenses of the body

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Microorganisms and Disease
Which of the following is true regarding anthrax?

Inhalation anthrax and cutaneous anthrax are caused by separate strains of Bacillus anthracis
Anthrax is highly contagious
Inhalation Anthrax requires infection with a large number of spores
Anthrax is caused by a virus

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Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

The most serious disease symptoms are the direct result of toxin action
Both organisms cause skin and respiratory tract infections
Both organisms are gram-positive spore formers
Diphtheria toxin and edema toxin are ADP ribosylating toxins

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Microorganisms and Disease
Type III secretion systems are used to inject "effector" proteins directly into a host cell. Salmonella uses a type III secretion system to help the pathogen to

survive the acid pH of the stomach
survive within macrophages
secrete LT (heat labile toxin) and ST (heat stable toxin) into the lumen of the intestine
activate T cells to proliferate and secrete cytokines

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Microorganisms and Disease
A major difference between EHEC and EPEC is

EHEC possesses a type III secretion system and EPEC does not
EPEC passes through the placenta to infect the fetus and EHEC does not
EHEC secretes a Shiga-like toxin and EPEC does not
EPEC rearranges host cell actin and EHEC does not

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