Enzymes The nucleophile in serine proteases is Asparagine both (a) and (b) Serine water Asparagine both (a) and (b) Serine water ANSWER DOWNLOAD EXAMIANS APP
Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to function as a proton shuttle neutralize the charge on the other's side chain keep the specificity pocket open clamp the substrate into the active site function as a proton shuttle neutralize the charge on the other's side chain keep the specificity pocket open clamp the substrate into the active site ANSWER DOWNLOAD EXAMIANS APP
Enzymes Before they can react, many molecules need to be destabilized. This state is typically achieved through oxidizing the molecules by removing electrons changing the reaction from a biosynthetic to a catabolic pathway changing the three-dimensional shape of the molecule the input of a small amount of activation energy oxidizing the molecules by removing electrons changing the reaction from a biosynthetic to a catabolic pathway changing the three-dimensional shape of the molecule the input of a small amount of activation energy ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences Both use nucleophilic attack to hydrolyze the peptide bond Both forms an acyl-enzyme intermediate Both require water to complete the catalytic cycle Both show specificity for certain amino acid sequences Both use nucleophilic attack to hydrolyze the peptide bond Both forms an acyl-enzyme intermediate ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the common features are shared between serine and aspartate proteases? All of these Both show specificity for certain amino acid sequences Both use a base to activate the nucleophile Both require water to complete the catalytic cycle All of these Both show specificity for certain amino acid sequences Both use a base to activate the nucleophile Both require water to complete the catalytic cycle ANSWER DOWNLOAD EXAMIANS APP
Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the size, shape, and charge of the active site or specificity pocket absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket size, shape, and charge of the active site or specificity pocket absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket ANSWER DOWNLOAD EXAMIANS APP
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