Enzymes
Which of the common features are shared between serine and aspartate proteases?

Both require water to complete the catalytic cycle
Both use a base to activate the nucleophile
Both show specificity for certain amino acid sequences
All of these

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Enzymes
Which of the following statements about enzymes or their function is true?

Enzymes speed up reactions by lowering activation energy
All of these
Enzymes are proteins whose three-dimensional form is key to their function
Enzymes do not alter the overall change in free energy for a reaction

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

presence of a low-barrier hydrogen bond in the active site or specificity pocket
proximity of Ser 195 to the active site or specificity pocket
size, shape, and charge of the active site or specificity pocket
absence of water in the active site

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