Enzymes
How is the enzyme COX-1 important in human health?

It catalyzes the production of hormones that maintain the stomach lining
It helps to transport carbon dioxide in the blood
It is critical for the biosynthesis of DNA
It is a chemical derivative of aspirin

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Enzymes
Before they can react, many molecules need to be destabilized. This state is typically achieved through

the input of a small amount of activation energy
changing the three-dimensional shape of the molecule
changing the reaction from a biosynthetic to a catabolic pathway
oxidizing the molecules by removing electrons

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Enzymes
Which of the following is false statement with regard to comparison between Serine and HIV proteases?

Both show specificity for certain amino acid sequences
Both require water to complete the catalytic cycle
Both use nucleophilic attack to hydrolyze the peptide bond
Both forms an acyl-enzyme intermediate

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

size, shape, and charge of the active site or specificity pocket
presence of a low-barrier hydrogen bond in the active site or specificity pocket
absence of water in the active site
proximity of Ser 195 to the active site or specificity pocket

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Enzymes
Which of the following statements about enzymes or their function is true?

Enzymes do not alter the overall change in free energy for a reaction
Enzymes speed up reactions by lowering activation energy
All of these
Enzymes are proteins whose three-dimensional form is key to their function

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