Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the presence of a low-barrier hydrogen bond in the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket size, shape, and charge of the active site or specificity pocket absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket size, shape, and charge of the active site or specificity pocket absence of water in the active site ANSWER DOWNLOAD EXAMIANS APP
Enzymes Common feature in all serine proteases is a hydrophobic specificity pocket cluster of reactive serine residues hydrophilic specificity pocket single reactive serine residue hydrophobic specificity pocket cluster of reactive serine residues hydrophilic specificity pocket single reactive serine residue ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both use nucleophilic attack to hydrolyze the peptide bond Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle Both forms an acyl-enzyme intermediate Both use nucleophilic attack to hydrolyze the peptide bond Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle Both forms an acyl-enzyme intermediate ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following (s) is/are serine proteases? all of these Elastase Trypsin Chymotrypsin all of these Elastase Trypsin Chymotrypsin ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the common features are shared between serine and aspartate proteases? Both require water to complete the catalytic cycle All of these Both show specificity for certain amino acid sequences Both use a base to activate the nucleophile Both require water to complete the catalytic cycle All of these Both show specificity for certain amino acid sequences Both use a base to activate the nucleophile ANSWER DOWNLOAD EXAMIANS APP
Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to clamp the substrate into the active site neutralize the charge on the other's side chain function as a proton shuttle keep the specificity pocket open clamp the substrate into the active site neutralize the charge on the other's side chain function as a proton shuttle keep the specificity pocket open ANSWER DOWNLOAD EXAMIANS APP
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