Enzymes The role of Asp 102 and His 57 during trypsin catalysis is to keep the specificity pocket open function as a proton shuttle neutralize the charge on the other's side chain clamp the substrate into the active site keep the specificity pocket open function as a proton shuttle neutralize the charge on the other's side chain clamp the substrate into the active site ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following is false statement with regard to comparison between Serine and HIV proteases? Both require water to complete the catalytic cycle Both use nucleophilic attack to hydrolyze the peptide bond Both forms an acyl-enzyme intermediate Both show specificity for certain amino acid sequences Both require water to complete the catalytic cycle Both use nucleophilic attack to hydrolyze the peptide bond Both forms an acyl-enzyme intermediate Both show specificity for certain amino acid sequences ANSWER DOWNLOAD EXAMIANS APP
Enzymes What is the specificity of the Clostripain protease? None of these It cleave after Lys residues It cleave after Arg residues It cleave after His residues None of these It cleave after Lys residues It cleave after Arg residues It cleave after His residues ANSWER DOWNLOAD EXAMIANS APP
Enzymes Which of the following (s) is/are serine proteases? Chymotrypsin all of these Trypsin Elastase Chymotrypsin all of these Trypsin Elastase ANSWER DOWNLOAD EXAMIANS APP
Enzymes The cleavage specificity of trypsin and chymotrypsin depend in part on the proximity of Ser 195 to the active site or specificity pocket absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket size, shape, and charge of the active site or specificity pocket proximity of Ser 195 to the active site or specificity pocket absence of water in the active site presence of a low-barrier hydrogen bond in the active site or specificity pocket size, shape, and charge of the active site or specificity pocket ANSWER DOWNLOAD EXAMIANS APP
Enzymes The proteolysis rate enhancement by chymotrypsin (~1010 folds) corresponds to a reduction in activation energy of about 40 kJ/mol 49 kJ/mol 58 kJ/mol 88 kJ/mol 40 kJ/mol 49 kJ/mol 58 kJ/mol 88 kJ/mol ANSWER DOWNLOAD EXAMIANS APP
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