Enzymes
The proteolysis rate enhancement by chymotrypsin (~1010 folds) corresponds to a reduction in activation energy of about

88 kJ/mol
40 kJ/mol
49 kJ/mol
58 kJ/mol

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Enzymes
The cleavage specificity of trypsin and chymotrypsin depend in part on the

size, shape, and charge of the active site or specificity pocket
presence of a low-barrier hydrogen bond in the active site or specificity pocket
absence of water in the active site
proximity of Ser 195 to the active site or specificity pocket

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Enzymes
Which of the following statements about enzymes or their function is true?

All of these
Enzymes do not alter the overall change in free energy for a reaction
Enzymes are proteins whose three-dimensional form is key to their function
Enzymes speed up reactions by lowering activation energy

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