Recombinant DNA Technology
Which of the following is correct in terms of determination of location of genetic traits?

Protein-coding genes are always associated with a restriction pattern
Restriction sites allow DNAs to be digested
None of these
Known protein coding sequences are too far apart to allow linkage determination for most new genes

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Recombinant DNA Technology
Some genetic diseases cannot be diagnosed by changes in restriction sites. Some of these can be detected by allele-specific oligonucleotide probes. These are

short sequences that will hybridize only to a specific base sequence
mutagenized copies of a gene
PCR-amplified variable numbers of tandem repeats (VNTRs)
copies of the gene with an altered sequence so that a restriction site is inserted

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Recombinant DNA Technology
A human cDNA library

contains DNA for virtually all of the human proteins in vectors
contains DNA for specific human proteins
cannot be used to obtain human genes because it would be radioactive
None of these

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