Cloning Vectors
Charon vectors are different from EMBL vectors because

physical separation of lambda arm from central fragment is required
physical separation of lambda arm from central fragment is not required
both (a) and (b)
they have more extensive range of restriction targets with in their polylinkers.

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Cloning Vectors
Cosmids lack

genes coding for viral proteins
marker genes coding for replication
cleavage site for the insertion of foreign DNA
origin of replication

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