Recombinant DNA Technology
Both DNA gel electrophoresis and SDS-PAGE of proteins are similar because

both techniques utilize the sieving properties of gels
All of these
in both cases molecules migrate to the anode
both techniques rely on a constant charge to mass ratio

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Recombinant DNA Technology
Knockout mice are created by

mutagenizing a mouse and selecting for mutant offspring
creating a chimera by fusing cells from two different cell lines
transfecting embryonic stem cells with an altered gene sequence
infecting the mouse with a retrovirus

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