Microorganisms and Disease
The "A" subunit of diphtheria toxin

lysis macrophages with the release of cytokines
forms cAMP that leads to fluid accumulation
cause ADP ribosylation of a factor involved in protein synthesis
binds host cell receptors found on heart cells

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Microorganisms and Disease
A major difference between EHEC and EPEC is

EPEC passes through the placenta to infect the fetus and EHEC does not
EHEC possesses a type III secretion system and EPEC does not
EPEC rearranges host cell actin and EHEC does not
EHEC secretes a Shiga-like toxin and EPEC does not

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