Microorganisms and Disease
Plastic implants can pose a serious nosocomial infection problem because

All of these
infected implants usually have to be surgically removed
phagocytes have trouble moving on the plastic surface
phagocytes have trouble engulfing bacteria embedded in a biofilm

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Microorganisms and Disease
Prontosil is

an effective antibacterial both in animals as well as in in-vitro cultures
an effective antibacterial when used in in-vitro cultures
an effective antibacterial when used in animals
not used as an antibacterial agent

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

cause ADP ribosylation of a factor involved in protein synthesis
binds host cell receptors found on heart cells
forms cAMP that leads to fluid accumulation
lysis macrophages with the release of cytokines

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