Microorganisms and Disease
Both Mycobacterium tuberculosis and Streptococcus pneumoniae

stay in the lung and rarely, if ever, enter the bloodstream
have cell walls that contain a high content of mycolic acids
have polysaccharide capsules
are acquired by inhalation

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

binds host cell receptors found on heart cells
forms cAMP that leads to fluid accumulation
lysis macrophages with the release of cytokines
cause ADP ribosylation of a factor involved in protein synthesis

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