Microorganisms and Disease
Both Mycobacterium tuberculosis and Streptococcus pneumoniae

stay in the lung and rarely, if ever, enter the bloodstream
have cell walls that contain a high content of mycolic acids
are acquired by inhalation
have polysaccharide capsules

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

binds host cell receptors found on heart cells
forms cAMP that leads to fluid accumulation
cause ADP ribosylation of a factor involved in protein synthesis
lysis macrophages with the release of cytokines

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Microorganisms and Disease
Which of the following characteristic of the Rotavirus was important for the construction of the Rotashield vaccine?

The possession of a segmented RNA genome
The ability of monkey Rotavirus strains to cause serious illness (diarrhea) in human beings
A limited number of capsule types
The ability of the Rotavirus to be transmitted faster

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Microorganisms and Disease
Which of the following is true regarding anthrax?

Anthrax is highly contagious
Inhalation anthrax and cutaneous anthrax are caused by separate strains of Bacillus anthracis
Anthrax is caused by a virus
Inhalation Anthrax requires infection with a large number of spores

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Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

Diphtheria toxin and edema toxin are ADP ribosylating toxins
Both organisms cause skin and respiratory tract infections
The most serious disease symptoms are the direct result of toxin action
Both organisms are gram-positive spore formers

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