Microorganisms and Disease
Both Mycobacterium tuberculosis and Streptococcus pneumoniae

have cell walls that contain a high content of mycolic acids
have polysaccharide capsules
are acquired by inhalation
stay in the lung and rarely, if ever, enter the bloodstream

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

lysis macrophages with the release of cytokines
binds host cell receptors found on heart cells
cause ADP ribosylation of a factor involved in protein synthesis
forms cAMP that leads to fluid accumulation

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Microorganisms and Disease
A major difference between EHEC and EPEC is

EHEC possesses a type III secretion system and EPEC does not
EPEC passes through the placenta to infect the fetus and EHEC does not
EPEC rearranges host cell actin and EHEC does not
EHEC secretes a Shiga-like toxin and EPEC does not

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