Microorganisms and Disease
Both Mycobacterium tuberculosis and Streptococcus pneumoniae

stay in the lung and rarely, if ever, enter the bloodstream
are acquired by inhalation
have polysaccharide capsules
have cell walls that contain a high content of mycolic acids

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

forms cAMP that leads to fluid accumulation
cause ADP ribosylation of a factor involved in protein synthesis
lysis macrophages with the release of cytokines
binds host cell receptors found on heart cells

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Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

Both organisms are gram-positive spore formers
The most serious disease symptoms are the direct result of toxin action
Both organisms cause skin and respiratory tract infections
Diphtheria toxin and edema toxin are ADP ribosylating toxins

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