Microorganisms and Disease
Both Mycobacterium tuberculosis and Streptococcus pneumoniae

are acquired by inhalation
have cell walls that contain a high content of mycolic acids
stay in the lung and rarely, if ever, enter the bloodstream
have polysaccharide capsules

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Microorganisms and Disease
Prontosil is

an effective antibacterial both in animals as well as in in-vitro cultures
an effective antibacterial when used in animals
an effective antibacterial when used in in-vitro cultures
not used as an antibacterial agent

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Microorganisms and Disease
Cholera toxin is an A-B type toxin in which the B portions bind to a receptor on a host cell and the A portion enters the cell to cause

cleavage of rRNA that results in disruption of ribosome function
ADP ribosylation of guanylate cyclase that stimulates production of cGMP
ADP ribosylation of adenylate cyclase that stops production of cAMP
ADP ribosylation of a G protein that locks it into an active form that stimulates adenylate cyclase to make cAMP

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

cause ADP ribosylation of a factor involved in protein synthesis
binds host cell receptors found on heart cells
lysis macrophages with the release of cytokines
forms cAMP that leads to fluid accumulation

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Microorganisms and Disease
A major difference between EHEC and EPEC is

EPEC rearranges host cell actin and EHEC does not
EHEC possesses a type III secretion system and EPEC does not
EHEC secretes a Shiga-like toxin and EPEC does not
EPEC passes through the placenta to infect the fetus and EHEC does not

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