Animal Cell Culture and Regulation
In animal cell culture, particularly mammalian cell culture, transformation means

phenotypic modifications of cells in culture
release of genetic information
uptake of new genetic material
both (a) and (b)

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Animal Cell Culture and Regulation
The major problem associated with the isolation of free cells and cell aggregates from organs is that of

disintegrating the cells from their supporting matrix
inhibiting the cells from their supporting matrix
releasing the cells from their supporting matrix
None of these

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