Recombinant DNA Technology
When populations are small, gene frequencies can change from generation to generation and some alleles may become fixed in a population. This is called __________ .

genetic drift
heterosis
inbreeding
assortative mating

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Recombinant DNA Technology
Isoschizomers recognize

different recognition site and different recognition sequence
same recognition site and recognition sequence
same recognition sequence but different recognition site
same recognition site and different recognition sequence

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Recombinant DNA Technology
Some genetic diseases cannot be diagnosed by changes in restriction sites. Some of these can be detected by allele-specific oligonucleotide probes. These are

short sequences that will hybridize only to a specific base sequence
copies of the gene with an altered sequence so that a restriction site is inserted
mutagenized copies of a gene
PCR-amplified variable numbers of tandem repeats (VNTRs)

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