Cloning Vectors
Phagemid consist of

plasmid vector carrying origin of replication of plasmid only
plasmid vector carrying λ attachment (λ att) site
plasmid vector carrying λ phage's cos site
plasmid vector carrying origin of replication of λ phage only

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Cloning Vectors
Cosmid vectors are

cryptic plasmids
plasmids that have no selection marker
phages that lack cos site
plasmids that contain fragment of λ DNA including the cos site

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Cloning Vectors
Cosmids lack

cleavage site for the insertion of foreign DNA
marker genes coding for replication
origin of replication
genes coding for viral proteins

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