Cell Signalling and Transduction
Nitroglycerin has long been administered to human patients suffering from chronic chest pain (angina). This medication works because it

breaks down into nitric oxide, which increases blood flow to the heart
is broken down into hormones that affect the heart
interferes with chemical cascades that trigger contraction of heart muscle
mimics the action of signal receptors

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Cell Signalling and Transduction
The binding of ligands to many G-proteins linked receptors leads to shortlived

decrease in the concentration of certain extracellular signaling molecules called first messenger
increase in the concentration of certain intracellular signaling molecules called second messenger
increase in the concentration of certain extracellular signaling molecules called first messenger
decrease in the concentration of certain intracellular signaling molecules called second messenger

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Cell Signalling and Transduction
Which of the following is true about a hydrophilic signaling molecule?

Its receptor is located in the cytosol of the target cell
It is a steroid
Since it can enter the cell, it directly affects some specific cell process
It might trigger a signal cascade that causes some effect in a cell

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Cell Signalling and Transduction
A signal cascade induced by adrenaline or thyroxine

All of these
results in the activation of a sequence of enzymes needed for the cell effect
must begin with receipt of the signal molecule by a surface receptor
involves the activation of a G protein

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