Microorganisms and Disease
Lactoferrin helps to protect against pathogens by

facilitating the growth of normal flora
sequestering Iron
lowering the pH
blocking sebum production

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Microorganisms and Disease
Which of the following is common in the disease caused by Coryne-bacterium diphtheriae and Bacillus anthracis?

Both organisms cause skin and respiratory tract infections
Both organisms are gram-positive spore formers
The most serious disease symptoms are the direct result of toxin action
Diphtheria toxin and edema toxin are ADP ribosylating toxins

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Microorganisms and Disease
The "A" subunit of diphtheria toxin

binds host cell receptors found on heart cells
lysis macrophages with the release of cytokines
forms cAMP that leads to fluid accumulation
cause ADP ribosylation of a factor involved in protein synthesis

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