Antigen
For specific antigen recognition by T cells,

antigen is bound by a T cell membrane antibody
antigen exposure during T cell maturation is required
MHC molecules are not required
denaturation of antigen does not reduce epitope recognition

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Antigen
During the lag period between antigen contact and detection of adaptive immunity,

innate immune effectors are eliminating antigen
new B and T cells with the appropriate antigen specificity must be produced in the bone marrow
antigen is hidden from the immune system in macrophages
innate immunity blocks the activation of adaptive immune effector cells

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