Antigen
Antigen, when injected in the body activates its specific lymphocytes in the

draining lymph nodes
spleen lymphoid tissue
MALT (mucosa associated
blood circulation

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Antigen
During the lag period between antigen contact and detection of adaptive immunity,

antigen is hidden from the immune system in macrophages
new B and T cells with the appropriate antigen specificity must be produced in the bone marrow
innate immunity blocks the activation of adaptive immune effector cells
innate immune effectors are eliminating antigen

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