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Disease Associated with Immune System

Disease Associated with Immune System
An example of an immunodeficiency disorder is

systemic lupus erythematosus
thyroiditis
AIDS
rheumatic fever

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Disease Associated with Immune System
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

IgG synthesis
macrophage activation to vesicular pathogens
CD8 T cell-mediated cytotoxicity
alternative complement activation.

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Disease Associated with Immune System
A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind

His or Pro
Ser or Thr
Leu or Ileu
Tyr or Phe

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Disease Associated with Immune System
DiGeorge's syndrome is characterized by the lack of a thymus The mouse model closest to this human disease would be a

knock-out mouse for a thymus
nude mouse
recombinant mouse for CD3
knock-out mouse for RAG-1 and RAG-2

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Disease Associated with Immune System
Retinoblastoma is due to a mutation in a

kinase
cyclin
viral gene
tumor supressor

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Disease Associated with Immune System
A selective IgA deficiency would be expected to result in problems with

mucosal pathogens
pathogens which can survive inside macrophages
infections following dental work due to bacteria entering the bloodstream
bacterial infections

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