Disease Associated with Immune System
Bone marrow given to an infant with SCID must

be irradiated to eliminate GVHD
come from a donor that shares some MHC alleles with the recipient
contain mature T cells that can begin making immune responses immediately
come from one of the child's parents

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Disease Associated with Immune System
Difficulties with somatic gene therapy arise from all of the following except

limited life span of more mature hematopoietic cells
transducing genetic material into stem cells
GVHD caused by mature T cells in the transplanted cells
inserting a gene so that it will function properly

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