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Structure and Properties of Peptides

Structure and Properties of Peptides
When pO2 = Kd of myoglobin, the fractional saturation (YO2) is about

0.1
0.9
0.5
1.7

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Structure and Properties of Peptides
What is the effect of a decrease in pH on hemoglobin oxygen affinity?

Increase affinity in muscle cell otherwise decrease
Increase in oxygen affinity
Decrease in oxygen affinity
No effect on oxygen affinity

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Structure and Properties of Peptides
Hydrogen bonds in a-helices are

roughly parallel to the helix axis
analogous to the steps in a spiral staircase
more numerous than Vander Waals interactions
not present at Phe residues

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Structure and Properties of Peptides
The molecular formula for glycine is C2H5O2N. What would be the molecular formula for a linear oligomer made by linking ten glycine molecules together by condensation synthesis?

C20H50O20N10
C20H40O10N10
C20H68O29N10
C20H32O11N10

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Structure and Properties of Peptides
What was the first protein whose complete tertiary structure was determined?

Myoglobin
Pancreatic ribonuclease
Pancreatic DNase
Lysozyme

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Structure and Properties of Peptides
The different orders of protein structure are determined by all of the following bond types except

peptide bonds
hydrogen bonds
phospho-diester bonds
disulfide bridges

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