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Structure and Properties of Peptides

Structure and Properties of Peptides
Disulfide bonds most often stabilize the native structure of

hydrophobic proteins
extracellular proteins
dimeric proteins
intracellular proteins

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Structure and Properties of Peptides
The peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala, was digested with cyanogen bromide (CNBr) to produce:

Val-Lys-Glu + Met-Ser-Trp-Arg-Ala
Val-Lys-Glu-Met-Ser-Trp + Arg-Ala
Val-Lys + Glu-Met-Ser + Trp-Arg-Ala
Val-Lys-Glu-Met + Ser-Trp-Arg-Ala

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Structure and Properties of Peptides
The peptide bond in proteins is

usually cis unless proline is the next amino acid
only found between proline residues
usually trans unless proline is the next amino acid
is planar because of steric hinderance

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Structure and Properties of Peptides
Peptides in the fully extended chain conformation

do not occur in nature
also have a cis geometry in their peptide bonds
have Y = F = 180°
are equivalent to the (3-sheet structure

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Structure and Properties of Peptides
The heme is held in place by a bond between

the Fe2+ and histidine
the Fe3+ and histidine
the Fe2+ and cysteine
the Fe3+ and cysteine

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Structure and Properties of Peptides
The oxygen in hemoglobin and myoglobin is bound to

the iron atom in the heme group
the nitrogen atoms on the heme
histidine residues in the protein
lysine residues in the protein

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MORE MCQ ON Structure and Properties of Peptides

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