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DNA Structure and Replication

DNA Structure and Replication
The nicks or gaps between Okazaki fragments are eventually sealed by

polymerase
DNA ligase
RNA ligase
gyrase

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DNA Structure and Replication
What is the name given to the points at which a DNA helix is unwound and new strands develop?

Replication forks
Replication origins
Leading strands
Okazaki fragments

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DNA Structure and Replication
What does ligase do during replication of DNA?

Synthesizes the lagging strand
Digests mRNA when it is no longer needed
Makes copies of mRNA from DNA
Joins nicks in DNA strands

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DNA Structure and Replication
The size of a linear DNA fragment in a gel can be estimated by

the time it takes the gel to run
fluorescence in UV light
comparison with a molecular weight standard such as Hind III digested phage lambda
the sedimentation coefficient

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DNA Structure and Replication
Which histone(s) are associated with the linker DNA of a nucleosome?

Histone H1
Histones H2A and H2B
Histone H4
Histone H3

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DNA Structure and Replication
The chromosomal DNA complexes with

five types of histone as H1, H2A, H2B, H3 and H4
three types of histone as H1, H2A and H4
four types of histone as H1, H2A, H3 and H4
two types of histone as H1 and H4

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