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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
The mode of action of polymyxin is to

injury to the plasma membrane
inhibit DNA synthesis
inhibit protein synthesis
inhibit folic acid synthesis

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Antimicrobial Chemotherapeutic Agents
The susceptibility of a microorganism to antibiotics and other chemotherapeutic agents can be determined by using

tube dilution technique
none of these
paper disk plate
both (a) and (b)

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Antimicrobial Chemotherapeutic Agents
Interference mechanism of ciprofloxacin and norfloxacin is due to their action on

DNA function
cell wall synthesis
cell membrane function
protein synthesis

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Antimicrobial Chemotherapeutic Agents
The scientist who first discovered the substance penicillin was

Alexander Fleming
Joseph Lister
none of these
Paul Ehrlich

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

are inactivated by β-lactamase
bind to and inactivate a bacterial protein
must be transported into the cytoplasm in order to act
inhibit the cross-linking of peptidoglycan

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Antimicrobial Chemotherapeutic Agents
The antibiotics not clinically useful for Pseudomonas aeruginosa infection is

piperacillin
ceftazidime
trimethoprim-sulphamethoxazole
aminoglycosides

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