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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
The larger the __________ , the better the chemotherapeutic agent.

selective toxicity
spectrum
therapeutic dose
therapeutic index

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Antimicrobial Chemotherapeutic Agents
Cycloserine inhibits

alanine racemase
D-alanyl - D-alanine synthetase
Both (a) and (b)
amidase

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Antimicrobial Chemotherapeutic Agents
Which is not an amino acid and peptide antibiotic?

Tetranactin
Actinomycin
Bacitracin
Penicillin

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Antimicrobial Chemotherapeutic Agents
The most selective antibiotics are those that interfere with the synthesis of

bacterial DNA
bacterial cell walls
bacterial RNA
bacterial plasma membrane

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

must be transported into the cytoplasm in order to act
inhibit the cross-linking of peptidoglycan
bind to and inactivate a bacterial protein
are inactivated by β-lactamase

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Antimicrobial Chemotherapeutic Agents
The nitrofurans differ from the antibiotics in that they

all of these
do not occur naturally
are antimicrobial drugs
occur naturally

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