Water, pH and Macromolecules
The effectiveness or capacity of a buffer solution can be affected by

temperature of buffer components
both (a) and (b)
concentration of the conjugate base to the weak acid
molar concentration of the buffer components

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Water, pH and Macromolecules
The main difference between an acid and a base is that

bases are polar molecules and acids are not
acids donate hydrogen ions in water while bases accept hydrogen ions
acids are polar molecules and bases are not
bases donate hydrogen ions in water while acids accept hydrogen ions

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