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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
The antibiotics not clinically useful for Pseudomonas aeruginosa infection is

aminoglycosides
ceftazidime
piperacillin
trimethoprim-sulphamethoxazole

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Antimicrobial Chemotherapeutic Agents
Which antibiotic has a beta-lactam ring?

Cephalosporin
Tetracycline
Streptomycin
Penicillin

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Antimicrobial Chemotherapeutic Agents
Amphotericin B and polymyxin interfere with

DNA function
cell membrane function
cell wall synthesis
protein synthesis

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

bind to and inactivate a bacterial protein
are inactivated by β-lactamase
inhibit the cross-linking of peptidoglycan
must be transported into the cytoplasm in order to act

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Antimicrobial Chemotherapeutic Agents
Which of the following may cause resistance to penicillin?

Impermeability of cell envelope
Alteration or lack of penicillin-binding proteins
All of these
Production of β-lactamases by bacteria

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Antimicrobial Chemotherapeutic Agents
Which of the following protein synthesis mechanisms may be affected by particular drugs?

Aminoacyl-tRNA binding
Peptide bond formation
All of these
mRNA translocation

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