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Monoclonal Antibodies

Monoclonal Antibodies
T cells are the source of

interleukin
interferon
all of these
lymphotoxin

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Monoclonal Antibodies
The Ig locus is about

l/3rd of all hybridomas
1/4th of all hybridomas
2/3rd of all hybridomas
l/2nd of all hybridomas

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Monoclonal Antibodies
Preliminary clinical results with a humanized antibody against the interleukin-2 receptor have suggested the

All of these
poor recognition of immunoglobulin, Ig constant regions
absence of human immune response against murine proteins (HAMA) response
presence of HAMA response

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Monoclonal Antibodies
The EBV-hybridoma technique

All of these
gives much higher hybridization frequencies
facilitates the proliferation of antigen specific B cells
immortalizes the donor Bcells

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Monoclonal Antibodies
The antigen-specific lymphocytes can be immortalized by which of the following method?

Hybridization with a suitable lymphoid tumor cell
Transformation following infection by Epstein-Barr virus (EB V)
All of these
Transfection with tumor derived DNA

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Monoclonal Antibodies
TC cells are important in controlling

all of these
allergy
autoimmunity
virus infections

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