Which of the following forces is the most unfavorable for protein folding? Conformational entropy Hydrophobic interactions Electrostatic interactions Vander Waals interactions TRUE ANSWER : ? YOUR ANSWER : ?
Attractive Vander Waals forces occur between apolar molecules in the liquid state any pair of nearby atoms only if other forces are less favorable polar molecules in the solid state TRUE ANSWER : ? YOUR ANSWER : ?
At the midpoint of a temperature transition curve, Keq = 1.0 and ΔG = 0 [Native] = [Unfolded] All of these half of the protein is denatured TRUE ANSWER : ? YOUR ANSWER : ?
For the unfolding reaction of Protein G, ΔH° =210.6 kJ/mol, this means that folding is favored enthalpically the entropy is negative at all temperatures the entropy is positive at all temperatures unfolding is favored enthalpically TRUE ANSWER : ? YOUR ANSWER : ?
Which of the following is the most correct? Charged amino acids are never buried in the interior of a protein All hydrophobic amino acids are buried when a protein folds Tyrosine is only found in the interior of proteins Charged amino acids are seldom buried in the interior of a protein TRUE ANSWER : ? YOUR ANSWER : ?
Unpaired H-bond donors and acceptors are found in the hydrophobic core of a protein only on Pro residues only at the ends of a-helices rarely only at the turns connecting p-strands TRUE ANSWER : ? YOUR ANSWER : ?
If the egg white protein, ovalbumin, is denatured in a hard-boiled egg, then which of the following is least affected? The secondary structure of ovalbumin The tertiary structure of ovalbumin The primary structure of ovalbumin The quaternary structure of ovalbumin TRUE ANSWER : ? YOUR ANSWER : ?
The correlation between free energy ΔG transfer between the aqueous/organic phases and the surface area of amino acid residues reflects the reduction in solvent-accessible area during protein folding is similar to effects seen with SDS denaturation is only meaningful for the polar amino acids ignores the important contribution of the peptide bond TRUE ANSWER : ? YOUR ANSWER : ?
Which of the following forces is the most favorable for protein folding? Hydrogen bonds Vander Waals interactions Conformational entropy Hydrophobic Interactions TRUE ANSWER : ? YOUR ANSWER : ?
Buried hydrophobic side chains in a globular protein fit into a hole formed by the side chains of 1-3 other amino acids 5-7 other amino acids 13-15 other amino acids 9-12 other amino acids TRUE ANSWER : ? YOUR ANSWER : ?