NETWORKS ANALYSIS AND SYNTHESIS QUIZ

Self reactive antibodies are not found in significant concentration in normal serum because

self reactive B cells are killed by CD8 T cells

self reactive B cells switch to IgA which is all secreted and not present in serum

B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide

it is impossible to generate a self-reactive antibody

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the following is the phylogenetically oldest immunoglobulin?

IgG

All are similar

IgM

IgE

TRUE ANSWER : ?
YOUR ANSWER : ?

Heat-labile class of immunoglobulins include

IgE

IgM

IgA

IgG

TRUE ANSWER : ?
YOUR ANSWER : ?

Antigen binding sites of an immunoglobulin are located in

Fab regions of the antibody

light chain alone

Fc region of the antibody

heavy chain alone

TRUE ANSWER : ?
YOUR ANSWER : ?

Which is not a function of IgA?

Fix complement

Protect eyes

Protect mucosal surfaces

Agglutinate antigen

TRUE ANSWER : ?
YOUR ANSWER : ?

The class of immunoglobulin, most abundant in body is

IgD

IgE

IgM

IgG

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the following theory of antibody production is most widely accepted?

Direct template theory

Side chain theory

Indirect template theory

Clonal selection theory

TRUE ANSWER : ?
YOUR ANSWER : ?

Which of the following (s) is/are function (s) of Fc fragment of IgG?

All of these

It is related to passage of IgG across the placental barrier

It binds complement

It determines catabolic rate

TRUE ANSWER : ?
YOUR ANSWER : ?

Anti-Rh antibodies are

IgD type

IgG type

IgE type

IgA type

TRUE ANSWER : ?
YOUR ANSWER : ?

Which is not a function of IgG?

Activates or fixes complement

Major antibody in serum

First antibody type produced against an antigen during the primary antibody response

Involved in opsonization

TRUE ANSWER : ?
YOUR ANSWER : ?

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