MICROORGANISMS AND DISEASE QUIZ

A major difference between EHEC and EPEC is

EPEC passes through the placenta to infect the fetus and EHEC does not

EHEC possesses a type III secretion system and EPEC does not

EPEC rearranges host cell actin and EHEC does not

EHEC secretes a Shiga-like toxin and EPEC does not

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Cholera toxin is an A-B type toxin in which the B portions bind to a receptor on a host cell and the A portion enters the cell to cause

cleavage of rRNA that results in disruption of ribosome function

ADP ribosylation of adenylate cyclase that stops production of cAMP

ADP ribosylation of guanylate cyclase that stimulates production of cGMP

ADP ribosylation of a G protein that locks it into an active form that stimulates adenylate cyclase to make cAMP

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The nature of the poliovirus gives for oral vaccination (satin vaccine) as part of the eradication programme is

live attenuated strains of all three immunological types

small dosage of wild-type live viruses

formalin-inactivated viruses

heat killed virus

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Each of the 3 virulence factors of Bacillus anthracis i.e. the capsule, edema toxin and lethal toxin can affect the activity of

ciliated epithelial cells

M cells

B cells

macrophages

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Which of the following is true regarding anthrax?

Anthrax is caused by a virus

Inhalation anthrax and cutaneous anthrax are caused by separate strains of Bacillus anthracis

Inhalation Anthrax requires infection with a large number of spores

Anthrax is highly contagious

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Coxsackie virus B3, a subgroup of enteroviruses, commonly causes

myocarditis

gastroenteritis

muscular dystrophy

acute hemorrhagic conjunctivitis

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The influenza vaccine is administered each year because

it is a polysaccharide vaccine that does not confer long-term protection

mutations in the viral hemagglutinin may allow the virus to evade the immune response elicited by previous vaccines

None of these

the vaccine is sufficiently toxic to make it necessary to administer only a small amount at any one time

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The agent responsible for causing mad cow disease is thought to be a

protozoan

prion

virus

fungus

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Fatalities following influenza infection are usually due to the

bacterial superinfection

damage to the heart muscle

formation of granulomas in the lung

dehydration

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In the human disease cholera, what is it that actually ends up killing the victim?

Too little water in the food stream

the toxin produced by the bacterium

Dehydration and loss of nutrients

Faulty carrier proteins

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