DISEASE ASSOCIATED WITH IMMUNE SYSTEM QUIZ

The chemical, typically released by the body in an allergic response is

perforins

antihistamines

histamine

allergens

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An example of an immunodeficiency disorder is

rheumatic fever

AIDS

systemic lupus erythematosus

thyroiditis

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DiGeorge's syndrome is characterized by the lack of a thymus The mouse model closest to this human disease would be a

recombinant mouse for CD3

knock-out mouse for a thymus

knock-out mouse for RAG-1 and RAG-2

nude mouse

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Specific translocations are associated with

pancreatic cancer

some leukemias

colon cancer

breast cancer

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A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind

Tyr or Phe

Leu or Ileu

Ser or Thr

His or Pro

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X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be

failure of Th2 cells to provide co-stimulation for B cell proliferation

activation of B cells by T-independent antigens

failure of Th2 cells to provide co-stimulation for B cell isotype switching

failure of B cells to provide co-stimulation for Th2 activation

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The HIV virus infects primarily

cells in the immune system

liver cells

brain cells

red blood cells

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Bone marrow given to an infant with SCID must

come from one of the child's parents

be irradiated to eliminate GVHD

contain mature T cells that can begin making immune responses immediately

come from a donor that shares some MHC alleles with the recipient

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The primary reason for AIDS, a deadly disease is that it

is caused by a virus

is caused by a bacterium

causes a breakdown of the body's inflammatory response

destroys key components of the body's internal defense system

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Infants are most susceptible to bacterial infection due to low circulating levels of IgG

in utero (before birth)

at 0-3 months of age

at 3-12 months of age

at 12-24 months of age

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