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Antibiotics

Antibiotics
Chlorotetracyclin is soluble in

organic solvents
water
all of these
ether

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Antibiotics
Which of the following precursor is added in the medium to get penicillin G?

Phenyl carbamic acid
Ammonium sulphate
Ammonium chloride
Phenyl acetic acid

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Antibiotics
Fermentation medium for oxytetracyclin (terramycin) consist of

CSL, (NH4)2 SO4, sodium chloride and CaCO3
CSL, starch,(NH4)2 SO4, ammonium chloride and CaCO3
CSL,(NH4)2 SO4, ammonium chloride and CaCO3
CSL, starch, (NH4)2 SO4, sodium chloride and CaCO3

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Antibiotics
High yield of chlorotetracyclin requires

controlled aeration
aeration which does not affect the yield
continuous aeration
no aeration

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Antibiotics
Which of the following changes occur during first phase of growth of Penicillium chrysogenum?

Growth of mycelia occurs
Ammonia is liberated in the medium
All of these
Lactic acid present in the corn steep liquor is utilized at the maximum rate

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Antibiotics
Antibiotics are typically produced in fed batch reactors because

All of these
antibiotic yields are generally higher when cell growth slows
the precursors are often toxic to the cells
antibiotic yields are generally higher when cells enter the stationary phase

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