Immune System
Which of the following proteins would not need localization signal?

A cell surface protein
A cytosolic protein
A nuclear protein
A protein bound to the endoplasmic reticulum (ER) membrane

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Immune System
Numerous antibodies can be prepared, against one antigen, each binds to unique epitopes. How is this antibody diversity generated?

By the combination of different heavy and light chains that form the antigen binding site
Both (a) and (b)
By rearrangements of the DNA encoding the variable regions of the heavy and light chains
Antibody proteins can physically change their shape to bind different epitopes

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Immune System
T cell receptors (or TCR) on CD4+ T cells

are secreted out into the environment to bind antigens
recognize peptides associated with MHC class I molecules
recognize peptides not associated with MHC molecules
recognize peptides associated with MHC class II molecules

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