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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
Which of the following protein synthesis mechanisms may be affected by particular drugs?

Peptide bond formation
mRNA translocation
All of these
Aminoacyl-tRNA binding

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Antimicrobial Chemotherapeutic Agents
Quinolones are

antimetabolites
penicillin derivatives
broad-spectrum
bacteriostatic

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Antimicrobial Chemotherapeutic Agents
The larger the __________ , the better the chemotherapeutic agent.

therapeutic index
spectrum
therapeutic dose
selective toxicity

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Antimicrobial Chemotherapeutic Agents
Amphotericin B and polymyxin interfere with

cell membrane function
protein synthesis
cell wall synthesis
DNA function

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Antimicrobial Chemotherapeutic Agents
Which of the following may cause resistance to penicillin?

All of these
Impermeability of cell envelope
Alteration or lack of penicillin-binding proteins
Production of β-lactamases by bacteria

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Antimicrobial Chemotherapeutic Agents
Which is not an amino acid and peptide antibiotic?

Penicillin
Actinomycin
Tetranactin
Bacitracin

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