DNA Structure and Replication
Which of the following is used to determine the appropriate stringency (Wallace rule)?

Tm = 69.3° + 0.41 (%)G+C -650/1
Tm = 2 x (No.of G:C base pair) + 4 x (No.of A:T base pair)
Tm = 4 x (No.of A:T base pair) + 2 x (No.of G:C base pair)
Tm = 4 x (No.of G:C base pair) + 2 x (No.of A:T base pair)

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DNA Structure and Replication
Nucleosome is

an hexamer of three histones without H1 protein
an octamer of four histones without H1 protein
an octamer of four histones with H1 protein
an hexamer of three histones with H1 protein

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DNA Structure and Replication
The rapid appearance of HIV-1 strains that are resistant to AIDS drugs is due in part to which of the following property of its reverse transcriptase?

It lacks a proofreading exonuclease
The RNase H domain of p66 causes error prone synthesis
It has low affinity for the correct dNTP's
AZT (zidovudine) is too expensive to be taken in effective doses

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