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Antimicrobial Chemotherapeutic Agents

Antimicrobial Chemotherapeutic Agents
Which of the following drugs involves modification of the drug by enzymatic modification or degradation of its active element to alter its/their resistance?

Aminoglyosides
All of these
Pencillins
Choloramphenicol

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Antimicrobial Chemotherapeutic Agents
The nitrofurans differ from the antibiotics in that they

do not occur naturally
occur naturally
all of these
are antimicrobial drugs

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Antimicrobial Chemotherapeutic Agents
The antibiotics which affords a broad spectrum of antimicrobial coverage against aerobic and anaerobic bacteria, rickettsiae, chlamydiae, and mycoplasmas is

metronidazole
gentamicin
tetracycline
vancomycin

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Antimicrobial Chemotherapeutic Agents
Quinolones are

penicillin derivatives
broad-spectrum
antimetabolites
bacteriostatic

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Antimicrobial Chemotherapeutic Agents
Both penicillin and fluoroquinolones

are inactivated by β-lactamase
bind to and inactivate a bacterial protein
must be transported into the cytoplasm in order to act
inhibit the cross-linking of peptidoglycan

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Antimicrobial Chemotherapeutic Agents
The third generation cephalosporin agents is

cefotaxime
cephalexin
cefoxitin
cephalothin

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