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Structure and Properties of Peptides

Structure and Properties of Peptides
Which hemoglobin chain replaces the beta chain in embryonic hemoglobulin?

Epsilon
Delta
Gamma
Alfa

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Structure and Properties of Peptides
The different orders of protein structure are determined by all of the following bond types except

hydrogen bonds
disulfide bridges
peptide bonds
phospho-diester bonds

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Structure and Properties of Peptides
Peptides in the fully extended chain conformation

have Y = F = 180°
are equivalent to the (3-sheet structure
also have a cis geometry in their peptide bonds
do not occur in nature

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Structure and Properties of Peptides
The same peptide, Val-Lys-Glu-Met-Ser-Trp-Arg-Ala. was digested with chymotrypsin to produce

Val-Lys-Glu-Met-Ser-Trp + Arg-Ala.
Val-Lys-Glu-Met + Ser-Trp-Arg-Ala.
Val-Lys + Glu-Met-Ser + Trp-Arg-Ala.
Val-Lys-Glu-Met-Ser + Trp-Arg-Ala.

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Structure and Properties of Peptides
What is the effect of a decrease in pH on hemoglobin oxygen affinity?

Increase in oxygen affinity
Decrease in oxygen affinity
Increase affinity in muscle cell otherwise decrease
No effect on oxygen affinity

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Structure and Properties of Peptides
The resonance structures that can be drawn for the peptide bond indicate that the peptide bond

has partial double bond character
is stronger than an ordinary single bond
is still not completely understood
both (a) and (b)

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