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Disorders in Biotechnology

Disorders in Biotechnology
What is the defective enzyme in the glycogen storage Von Gierke's disease?

Phosphofructokinase
None of these
Phosphorylase
Glucose-6-phosphatase

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Disorders in Biotechnology
A deficiency of the enzyme Hypoxanthine Guanine phosphoribosyl transferase (HGPRT) may cause

Lesch- Nyhan syndrome
Ehlers-Danlos syndrome
Kleinefelter's syndrome
Gaucher's disease

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Disorders in Biotechnology
Klinefelter syndrome is a manifestation of which chromosome aneuploidy?

None of these
XXX
XYY
XXY

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Disorders in Biotechnology
Which of the modification in hemoglobin is the cause of sickle cell anemia?

None of these
A deletion in the beta chain
A mutation in the beta chain
Replacement of the B chain by D chain

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Disorders in Biotechnology
If the RBC of human were kept in 0.9% NaCl solution, what sort of change will occur to RBC?

Cell will Burst
RBC will destroy
Cell will shrink
No change to RBC

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Disorders in Biotechnology
During sickle cell anemia which of the following takes place?

Glutamic acid change to aspartic acid
Glutamine change to valine
Valine change to glutamine
Aspartic acid change to glutamic acid

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