DNA Structure and Replication
The RNA primers used to initiate replication in E. coli

are joined together by DNA ligase
result in Okazaki fragments on leading strand
are removed by helicase + ATP
are removed by Pol I

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DNA Structure and Replication
In DNA, nucleotides are covalently joined together by

3', 4' phosphodiester bonds to form a repetitive sugar-phosphate chain
2', 3' phosphodiester bonds to form a repetitive sugar-phosphate chain
2', 5' phosphodiester bonds to form a repetitive sugar-phosphate chain
3', 5' phosphodiester bonds to form a repetitive sugar-phosphate chain

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