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ATP Synthesis and Fatty Acid Oxidation

ATP Synthesis and Fatty Acid Oxidation
The maximum energy per gram on oxidization is yielded from

starch
glycogen
protein
fat

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ATP Synthesis and Fatty Acid Oxidation
Where the acyl-CoA formed in the cytosol is transported for oxidation?

Microsomes
Remains in cytosol
Mitochondrial matrix
Endoplasmic reticulum

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ATP Synthesis and Fatty Acid Oxidation
The irreversibility of the thiokinase reactions (formation of initial acyl-CoA)

make this activation reaction the committed step on the pathway
is due to the subsequent hydrolysis of the product
applies only to even-chain fatty acids
both (a) and (b)

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ATP Synthesis and Fatty Acid Oxidation
Membrane potential and the proton gradient

reinforce one another when respiratory inhibitors are present
cancel one another when uncouplers are present
are both required to make ATP
are sufficient, separately, to make ATP from ADP + Pi;

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ATP Synthesis and Fatty Acid Oxidation
The oxidation of methanol (wood alcohol) in human retina tissue leads directly to the formation of

formaldehyde
none of these
CO2
sugars

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ATP Synthesis and Fatty Acid Oxidation
Each cycle of β-oxidation produces

1 FADH2, 1 NADH and 1 acetyl-CoA
1 FADH2, 1 NADH and 2 CO2 molecules
1 FADH2, 1 NAD+, and 1 acetyl-CoA
1 FAD, 1 NAD+ and 2 CO2 molecules

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