Protein Synthesis
Ribosomes select the correct tRNAs

depending on their abundance in the cytosol
solely on the basis of their anticodons
then bind to the appropriate mRNA
with the least abundant anticodons

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Protein Synthesis
The first step in translation is

binding of mRNA to the two ribosomal subunits
binding of mRNA to the small ribosomal subunit
binding of the two ribosomal subunits to each other
binding of tRNA to the small ribosomal subunit

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