Glycolysis
Phosphofructokinase, the major flux-controlling enzyme of glycolysis is allosterically inhibited and activated respectively by

AMP and Pi
ATP and PEP
ATP and ADP
Citrate and ATP

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Glycolysis
Which of the following is not a mechanism for altering the flux of metabolites through the rate-determining step of a pathway?

Genetic control of the enzyme concentration
Covalent modification of the enzyme
Diffusional coupling between adjacent active sites
Allosteric control of the enzyme activity

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Glycolysis
Why does the glycolytic pathway continue in the direction of glucose catabolism?

The enzymes of glycolysis only function in one direction
There are essentially three irreversible reactions that act as the driving force for the pathway
High levels of ATP keep the pathway going in a forward direction
Glycolysis occurs in either direction

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