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ATP Synthesis and Fatty Acid Oxidation

ATP Synthesis and Fatty Acid Oxidation
Long-chain fatty acids are oxidized step-wise in one carbon units starting from the

aliphatic end
both (a) and (b)
none of these
carboxyl end

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ATP Synthesis and Fatty Acid Oxidation
How many molecules of acetyl-CoA are produced in oxidation of palmitic acid (C16), which involves seven rounds of oxidation?

7
9
6
8

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ATP Synthesis and Fatty Acid Oxidation
The oxidation of methanol (wood alcohol) in human retina tissue indirectly leads to

colour blindness
pressure builds up
blindness
all of these

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ATP Synthesis and Fatty Acid Oxidation
Membrane potential and the proton gradient

are both required to make ATP
cancel one another when uncouplers are present
reinforce one another when respiratory inhibitors are present
are sufficient, separately, to make ATP from ADP + Pi;

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ATP Synthesis and Fatty Acid Oxidation
The irreversibility of the thiokinase reactions (formation of initial acyl-CoA)

make this activation reaction the committed step on the pathway
is due to the subsequent hydrolysis of the product
applies only to even-chain fatty acids
both (a) and (b)

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ATP Synthesis and Fatty Acid Oxidation
The transport of acyl-CoA for oxidation using a shuttle involves formation of the intermediate

acyl-carnitine
3 acetyl-CoA
Acyl-coenzyme A
None of these

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